Iakoucheva Lab

University of California - San Diego, Department of Psychiatry

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  • POSTDOCTORAL POSITIONS are available in the laboratory of Dr. Lilia Iakoucheva at the University of California, San Diego

    POSTDOCTORAL FELLOW - GENOMICS AND GENETICS OF NEUROPSYCHIATRIC DISORDERS

    A postdoctoral position is open to applicants with strong computational biology/systems biology/bioinformatics/statistics/networks backgrounds who are interested in applying their experience to study psychiatric disorders (autism and schizophrenia). The focus of the project is to utilize heterogeneous high-throughput datasets (WES, WGS, RNA-Seq, proteomics) to discover druggable networks and pathways involved in the brain disorders.

    Qualified candidates must have a PhD and a demonstrated strong ability in bioinformatics, systems biology, sequence analyses, network analyses or genetics including expertise in high-throughput data analyses, such as RNA-Seq, ChIP-Seq, CLIP-Seq, epigenomics, NGS, proteomics. Strong programming skills (Python, Java, R, C++ and Unix/Linux shell) are required. The candidate should also be familiar with NGS algorithms and tools, such as Bowtie, cufflinks, BWA, STAR, RSEM, UCSC Genome Browser, samtools, bedtools, vcf-tools etc. The knowledge of machine learning (deep learning, SVM and Bayesian inference) is a plus.

    The successful candidate should have a demonstrated ability for independent and critical thinking, excellent communication and teamwork skills, and strong publication record (at least one first-author publication is required). Please send a resume and a brief statement summarizing research interests and experience to lilyak@ucsd.edu


    POSTDOCTORAL FELLOW - MOLECULAR AND CELLULAR NEUROBIOLOGY

    A postdoctoral position is available in Dr. Iakoucheva lab for research into the molecular basis of autism and schizophrenia. The goal of the research program is to achieve better understanding of the functional impact of genetic mutations on molecular and cellular neuronal pathways. This position is open to applicants with extensive laboratory experience who are able to employ cutting-edge molecular and cellular approaches to investigation of psychiatric diseases.

    Qualified candidates must have a Ph.D. in Neuroscience, Molecular or Cellular Biology, Genetics, Biochemistry or related field and a solid lab experience including sound scientific practice in research, methodology development and accurate laboratory techniques. Candidate must have strong ability to design, organize, and coordinate scientific research projects as well as to supervise and train rotation students. Interest in writing independent grant applications and prior writing experience is favorable.

    Preference will be given to applicants who have a strong record of research in one or more of the following areas: CRISPR/Cas genome editing, cell culture including neuronal, gene expression (RNAseq), miRNA targets, cell-based functional assays, yeast and mammalian two-hybrid approaches for protein-protein, protein-DNA and protein-RNA interactions screening. Experience with common bioinformatics methods, in particular with genome sequencing and RNAseq data interpretation is desired.

    The successful candidate should have a demonstrated ability for independent and critical thinking, excellent communication and teamwork skills, and strong publication record (at least one first-author publication is required). Please send a resume and a brief statement summarizing research interests and experience to lilyak@ucsd.edu